Development and Validation of rp-HPLC Method of Cabozantinib in Active Pharmaceutical Ingredient and Pharmaceutical Dosage form
نویسندگان
چکیده
منابع مشابه
RP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms
A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...
متن کاملRP-HPLC method development and validation for determination of eptifibatide acetate in bulk drug substance and pharmaceutical dosage forms
A new, rapid, economical and isocratic reverse phase high performance liquid chromatography (RP-HPLC) method was developed for the determination of eptifibatide acetate, a small synthetic antiplatelet peptide, in bulk drug substance and pharmaceutical dosage forms. The developed method was validated as per of ICH guidelines. The chromatographic separation was achieved isocratically on C18 colum...
متن کاملSimultaneous RP-HPLC and UV Spectroscopic Method Development and Validation for Estimation of Ibandronate Sodium in Bulk and Pharmaceutical Dosage Form
The present study describes a simple, accurate, precise and cost effective UV-Vis Spectroscopic and RP-HPLC method for the estimation of Ibandronate sodium (IBN). The determination of Ibandronate sodium (IBN) was performed by both UV and RP-HPLC method using 215 nm as the determination wavelength. The drug was dissolved in NaOH solution (0.1N NaOH) for estimation in UV and in distilled water fo...
متن کاملMethod Development And Validation Of Ondansetron In Bulk And Pharmaceutical Dosage Form By Stability- Indicating RP-HPLC Method
A precise and feasible high-performance liquid chromatographic (HPLC) method for the analysis of antiemetic drug Ondansetron tablet dosage form has been developed. The analysis was carried out on a zodiac C18 (4.6 x 250mm, 5 mm) column, using a buffer (pH 2.2), acetonitrile (73:27) as the mobile phase using a low pressure gradient mode with flow rate at 1ml/min and analysis was performed at wav...
متن کاملDevelopment and Validation of RP-HPLC Method for Determination of Glibenclamide in Pharmaceutical Dosage Forms
A rapid, linear, precise, selective and accurate reverse phase HPLC method was developed and validated for simultaneous estimation of glibenclamide in tablet dosage form. The method employed for analysis using methanol as a solvent. The wavelength UV 300 nm was selected for estimation and linearity was observed in the concentration range of 160 240 μg/ml for glibenclamide respectively. The reco...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research International
سال: 2021
ISSN: 2456-9119
DOI: 10.9734/jpri/2021/v33i1131247